The logo is a play on the "internationally recognised" symbol of care and hearing, transforming it into a stylised cross in two shades of blue. The flow of each shape suggests progression, the soft lines denote caring, and the clean form reflects the "professionalism and high standards of technology and expertise".

In 1997, the hospital moved to a new building in Simei and became known as the Changi General Hospital. The logo was retained despite the change in name.